Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer’s Disease and Identifying Promising Drug Targets
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as Alzheimer’s disease (AD). Injury to synapses and neurons and accumulation of extracellular amyloid plaques and intrace...
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Format: | Article |
Language: | English |
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MDPI AG
2022-11-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/12/11/1676 |