R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes. However, NGS profiling of liquid biopsies risk for false positive and false negative calls...

Full description

Bibliographic Details
Main Authors: Roberto Serna-Blasco, Estela Sánchez-Herrero, María Berrocal Renedo, Silvia Calabuig-Fariñas, Miguel Ángel Molina-Vila, Mariano Provencio, Atocha Romero
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biology
Subjects:
NGS
ctDNA
VAF
liquid biopsy
filtering
variant calling
Online Access:https://www.mdpi.com/2079-7737/10/10/954

Internet

https://www.mdpi.com/2079-7737/10/10/954

Similar Items