The Brown Alga Stypopodium zonale (Dictyotaceae): A Potential Source of Anti-Leishmania Drugs

The Brown Alga Stypopodium zonale (Dictyotaceae): A Potential Source of Anti-Leishmania Drugs

This study evaluated the anti-Leishmania amazonensis activity of a lipophilic extract from the brown alga Stypopodium zonale and atomaric acid, its major compound. Our initial results revealed high inhibitory activity for intracellular amastigotes in a dose-dependent manner and an IC50 of 0.27 μg/mL...

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Bibliographic Details
Main Authors: Deivid Costa Soares, Marcella Macedo Szlachta, Valéria Laneuville Teixeira, Angelica Ribeiro Soares, Elvira Maria Saraiva
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Marine Drugs
Subjects:
marine natural products
meroditerpenes
Stypopodium zonale
leshmanicidal activity
Online Access:http://www.mdpi.com/1660-3397/14/9/163

Internet

http://www.mdpi.com/1660-3397/14/9/163

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