Testing stem cell therapy in a rat model of inflammatory bowel disease: role of bone marrow stem cells and stem cell factor in mucosal regeneration.

BACKGROUND: The gastrointestinal (GI) mucosal cells turnover regularly under physiological conditions, which may be stimulated in various pathological situations including inflammation. Local epithelial stem cells appear to play a major role in such mucosal renewal or pathological regeneration. Less...

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Bibliographic Details
Main Authors: Bo Qu, Guo-Rong Xin, Li-Xia Zhao, Hui Xing, Li-Ying Lian, Hai-Yan Jiang, Jia-Zhao Tong, Bei-Bei Wang, Shi-Zhu Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4195572?pdf=render