Platelet-rich plasma decreases fibroblastic activity and woven bone formation with no significant immunohistochemical effect on long-bone healing: An experimental animal study with radiological outcomes

Purpose: This study aimed to analyze the immunohistochemical effect of platelet-rich plasma (PRP) on healing of long-bone fractures in terms of bone morphogenetic protein-2 (BMP-2), vascular endothelial growth factor (VEGF), the Ki-67 proliferation index, and radiological and histological analyses....

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Bibliographic Details
Main Authors: İbrahim Deniz Canbeyli, Rahmi Can Akgun, Orcun Sahin, Aysen Terzi, İsmail Cengiz Tuncay
Format: Article
Language:English
Published: SAGE Publishing 2018-10-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/2309499018802491