Playing Hide and Seek: How Glycosylation of the Influenza Virus Hemagglutinin Can Modulate the Immune Response to Infection

Seasonal influenza A viruses (IAV) originate from pandemic IAV and have undergone changes in antigenic structure, including addition of glycans to the hemagglutinin (HA) glycoprotein. The viral HA is the major target recognized by neutralizing antibodies and glycans have been proposed to shield anti...

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Bibliographic Details
Main Authors: Michelle D. Tate, Emma R. Job, Yi-Mo Deng, Vithiagaran Gunalan, Sebastian Maurer-Stroh, Patrick C. Reading
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/3/1294