Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs.

Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers for diseases. While reverse transcriptase Real-time PCR (RT-qPCR) is consid...

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Bibliographic Details
Main Authors: Helena Kelly, Tim Downing, Nina L Tuite, Terry J Smith, Michael J Kerin, Róisín M Dwyer, Eoin Clancy, Thomas Barry, Kate Reddington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4565682?pdf=render