Tamoxifen Delivery System Based on PEGylated Magnetic MCM-41 Silica

Tamoxifen Delivery System Based on PEGylated Magnetic MCM-41 Silica

Magnetic iron oxide containing MCM-41 silica (MM) with ~300 nm particle size was developed. The MM material before or after template removal was modified with NH<sub>2</sub>- or COOH-groups and then grafted with PEG chains. The anticancer drug tamoxifen was loaded into the organic groups...

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Bibliographic Details
Main Authors: Margarita Popova, Neli Koseva, Ivalina Trendafilova, Hristina Lazarova, Violeta Mitova, Judith Mihály, Denitsa Momekova, Georgi Momekov, Iskra Z. Koleva, Hristiyan A. Aleksandrov, Georgi N. Vayssilov, Ágnes Szegedi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
tamoxifen
mesoporous magnetic nanoparticles
PEGylation
release properties
DFT calculations
Online Access:https://www.mdpi.com/1420-3049/25/21/5129

Internet

https://www.mdpi.com/1420-3049/25/21/5129

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