S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes

S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes

Background: Adiponectin (Adn), released by adipocytes and other cell types such as skeletal muscle, has insulin-sensitizing and anti-inflammatory properties. Sphingosine 1-phosphate (S1P) is reported to act as effector of diverse biological actions of Adn in different tissues. S1P is a bioactive sph...

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Bibliographic Details
Main Authors: Caterina Bernacchioni, Roberta Squecco, Tania Gamberi, Veronica Ghini, Fabian Schumacher, Michele Mannelli, Rachele Garella, Eglantina Idrizaj, Francesca Cencetti, Elisa Puliti, Paola Bruni, Paola Turano, Tania Fiaschi, Chiara Donati
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
adiponectin
sphingosine kinase
skeletal muscle
sphingosine 1-phosphate
electrophysiological properties
NMR metabolomics
Online Access:https://www.mdpi.com/2073-4409/11/4/713

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https://www.mdpi.com/2073-4409/11/4/713

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