<i>E</i>-Cyanoacrylamides and 5-Imino Pyrrolones against <i>Trypanosoma cruzi</i>: Activity and Induced Mechanisms of Cell Death

<i>E</i>-Cyanoacrylamides and 5-Imino Pyrrolones against <i>Trypanosoma cruzi</i>: Activity and Induced Mechanisms of Cell Death

Chagas disease is caused by a protozoan parasite called <i>Trypanosoma cruzi</i>. The infection produces a first clinical phase, commonly asymptomatic or showing non-specific symptoms, and a second chronic phase characterized by cardiac and digestive dysfunctions in some individuals with...

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Bibliographic Details
Main Authors: Carlos J. Bethencourt-Estrella, Samuel Delgado-Hernández, Atteneri López-Arencibia, Irene Serafín-Pérez, Paula Rodríguez-Santana, Sara Rodríguez-Camacho, Carolina Fernández-Serafín, David Tejedor, Jacob Lorenzo-Morales, José E. Piñero
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Tropical Medicine and Infectious Disease
Subjects:
<i>Trypanosoma cruzi</i>
cyanoacrilamides
iminopirrolones
chemoterapy
Chagas
programmed cell death
Online Access:https://www.mdpi.com/2414-6366/9/9/191

Internet

https://www.mdpi.com/2414-6366/9/9/191

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