Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration

Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration

The promise of regeneration therapy for restoration of damaged myocardium after cardiac ischemic injury relies on targeted delivery of proliferative molecules into cardiomyocytes whose healing benefits are still limited owing to severe immune microenvironment due to local high concentration of proin...

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Bibliographic Details
Main Authors: Qiaozi Wang, Yanan Song, Jinfeng Gao, Qiyu Li, Jing Chen, Yifang Xie, Zhengmin Wang, Haipeng Tan, Hongbo Yang, Ning Zhang, Juying Qian, Zhiqing Pang, Zheyong Huang, Junbo Ge
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Myocardial infarction
Cardiac regeneration
Biomimetic nanoparticles
Neutrophils
Immunity restoration
MicroRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523003271

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http://www.sciencedirect.com/science/article/pii/S2211383523003271

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