Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case study

Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case study

BACKGROUND: Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16). These compounds were designed to have improved bioavailability whe...

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Bibliographic Details
Main Authors: Lisa Repsold, Thandi Mqoco, Elize Wolmarans, Sandra Nkandeu, Joji Theron, Tomek Piorkowski, Peet du Toit, Dirk van Papendorp, Annie Margaretha Joubert
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Biological Research
Subjects:
Whole blood
Morphology
ESE-15-ol
ESE-16
Anticancer
Erythrocytes
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100039&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100039&lng=en&tlng=en

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