UPF3B modulates endoplasmic reticulum stress through interaction with inositol-requiring enzyme-1α

UPF3B modulates endoplasmic reticulum stress through interaction with inositol-requiring enzyme-1α

Abstract The unfolded protein response (UPR) is a conserved and adaptive intracellular pathway that relieves the endoplasmic reticulum (ER) stress by activating ER transmembrane stress sensors. As a consequence of ER stress, the inhibition of nonsense-mediated mRNA decay (NMD) is due to an increase...

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Bibliographic Details
Main Authors: XingSheng Sun, Ruqin Lin, Xinxia Lu, Zhikai Wu, Xueying Qi, Tianqing Jiang, Jun Jiang, Peiqiang Mu, Qingmei Chen, Jikai Wen, Yiqun Deng
Format: Article
Language:English
Published: Nature Publishing Group 2024-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06973-3

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https://doi.org/10.1038/s41419-024-06973-3

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