Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

Abstract Background It is well established that obesity is associated with dysregulation of the ratio between the two major adipokines leptin and adiponectin. Furthermore, it was recently reported that maternal obesity has a significant impact on placental development. Leptin and adiponectin are pre...

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Bibliographic Details
Main Authors: Perrine Nogues, Esther Dos Santos, Hélène Jammes, Paul Berveiller, Lucie Arnould, François Vialard, Marie-Noëlle Dieudonné
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Clinical Epigenetics
Subjects:
Maternal obesity
Placenta
DNA methylation
Leptin
Adiponectin
Online Access:http://link.springer.com/article/10.1186/s13148-019-0612-6

Internet

http://link.springer.com/article/10.1186/s13148-019-0612-6

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