Ehf and Fezf2 regulate late medullary thymic epithelial cell and thymic tuft cell development

Ehf and Fezf2 regulate late medullary thymic epithelial cell and thymic tuft cell development

Thymic epithelial cells are indispensable for T cell maturation and selection and the induction of central immune tolerance. The self-peptide repertoire expressed by medullary thymic epithelial cells is in part regulated by the transcriptional regulator Aire (Autoimmune regulator) and the transcript...

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Bibliographic Details
Main Authors: Sören Lammers, Victor Barrera, Philip Brennecke, Corey Miller, Joon Yoon, Jared Balolong, Mark S. Anderson, Shannan Ho Sui, Lars M. Steinmetz, Ulrich H. von Andrian, Kristin Rattay
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
thymus
central tolerance
medullary thymic epithelial cell
Tuft cells
Fezf2
Ehf
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277365/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277365/full

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