Pregnancy is associated with decreased cardiac proteasome activity and oxidative stress in mice.

During pregnancy, the heart develops physiological hypertrophy. Proteasomal degradation has been shown to be altered in various models of pathological cardiac hypertrophy. Since the molecular signature of pregnancy-induced heart hypertrophy differs significantly from that of pathological heart hyper...

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Bibliographic Details
Main Authors: Andrea Iorga, Shannamar Dewey, Rod Partow-Navid, Aldrin V Gomes, Mansoureh Eghbali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3499532?pdf=render