Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigens

Pharmacodynamic assessment of T-cell-based cancer immunotherapies often focus on detecting rare circulating T-cell populations. The therapy-induced immune cells in blood-derived clinical samples are often present in very low frequencies and with the currently available T-cell analytical assays, ampl...

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Bibliographic Details
Main Authors: Michail Angelos Pavlidis, Nadia Viborg, Mads Lausen, Birgitte Rønø, Daniela Kleine-Kohlbrecher
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1404121/full