Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections

Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections

Implant-associated infections (IAIs) caused by biofilm formation are the most devastating complications of orthopedic surgery. Statins have been commonly and safely used drugs for hypercholesterolemia for many years. Here, we report that simvastatin-hydroxyapatite-coated titanium alloy prevents biof...

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Bibliographic Details
Main Authors: Tiantong Sun, Jie Huang, Wang Zhang, Xuanqi Zheng, Hong Wang, Jing Liu, Huijie Leng, Wanqiong Yuan, Chunli Song
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Bioactive Materials
Subjects:
Implant-associated infections
Simvastatin
Antibacterial
Biofilm
Osteogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22003309

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http://www.sciencedirect.com/science/article/pii/S2452199X22003309

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