Mosaic vaccine-induced antibody-dependent cellular phagocytosis associated with delayed HIV-1 viral load rebound post treatment interruption

Summary: A heterologous Ad26/MVA vaccine was given prior to an analytic treatment interruption (ATI) in people living with HIV-1 (mainly CRF01_AE) who initiated antiretroviral treatment (ART) during acute HIV-1. We investigate the impact of Ad26/MVA vaccination on antibody (Ab)-mediated immune respo...

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Bibliographic Details
Main Authors: Thembi Mdluli, Bonnie M. Slike, Daniel J. Curtis, Zhanna Shubin, Ursula Tran, Yifan Li, Vincent Dussupt, Letzibeth Mendez-Rivera, Suteeraporn Pinyakorn, Daniel J. Stieh, Frank L. Tomaka, Hanneke Schuitemaker, Maria G. Pau, Donn J. Colby, Eugène Kroon, Carlo Sacdalan, Mark de Souza, Nittaya Phanupak, Denise C. Hsu, Jintanat Ananworanich, Julie A. Ake, Lydie Trautmann, Sandhya Vasan, Merlin L. Robb, Shelly J. Krebs, Dominic Paquin-Proulx, Morgane Rolland
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724006727