Early diagnosis of congenital toxoplasmosis in newborn infants using IgG subclasses against two Toxoplasma gondii recombinant proteins

Early diagnosis of congenital toxoplasmosis in newborn infants using IgG subclasses against two Toxoplasma gondii recombinant proteins

The aim of this work was to evaluate the utility of ELISA-based testing of total IgG (IgGt) antibodies and its subclasses (IgG1, IgG2, IgG3 and IgG4) against soluble (STAg) and recombinant (rSAG1 and rMIC3) antigens of Toxoplasma gondii for diagnosing congenital toxoplasmosis. Sera from 217 newborns...

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Bibliographic Details
Main Authors: Carlos Henryque de Souza e Silva, Gláucia Queiroz de Andrade, José Nélio Januário, Ana Carolina de Aguiar Vasconcelos Carneiro, Mariangela Carneiro, Daniel Vitor Vasconcelos-Santos, Ricardo Wagner de Almeida Vitor
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2012-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
congenital toxoplasmosis
ELISA
recombinant proteins
IgG subclasses
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000300008&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000300008&lng=en&tlng=en

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