NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide

NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide

Abstract Background Inflammatory micro-environment has been proposed to play a critical role in lung tumorigenesis. NLRP3 is known as an intracellular receptor involving inflammation and has been reported which is increasingly associated with tumor development, but the role in inflammation-driven lu...

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Bibliographic Details
Main Authors: Li Huang, Shuyin Duan, Hua Shao, Aihua Zhang, Shuang Chen, Peng Zhang, Na Wang, Wei Wang, Yongjun Wu, Jing Wang, Hong Liu, Wu Yao, Qiao Zhang, Feifei Feng
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Respiratory Research
Subjects:
Benzo(a)pyrene
Lipopolysaccharide
Lung tumorigenesis
Inflammation
NLRP3
Online Access:http://link.springer.com/article/10.1186/s12931-019-0983-4

Internet

http://link.springer.com/article/10.1186/s12931-019-0983-4

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