A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.
X-chromosome inactivation, which occurs in female eutherian mammals is controlled by a complex X-linked locus termed the X-inactivation center (XIC). Previously it was proposed that genes of the XIC evolved, at least in part, as a result of pseudogenization of protein-coding genes. In this study we...
Główni autorzy: | , , , , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2008-06-01
|
Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC2430539?pdf=render |