A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.

X-chromosome inactivation, which occurs in female eutherian mammals is controlled by a complex X-linked locus termed the X-inactivation center (XIC). Previously it was proposed that genes of the XIC evolved, at least in part, as a result of pseudogenization of protein-coding genes. In this study we...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Eugeny A Elisaphenko, Nikolay N Kolesnikov, Alexander I Shevchenko, Igor B Rogozin, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2008-06-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC2430539?pdf=render