Maintenance of Functional Human Cancellous Bone and Human Hematopoiesis in NOD/SCID Mice

Attempts were made to establish models to study interactions between marrow stromal cells and hematopoietic cells in vivo. The approach was to create a NOD-SCID-hu murine model of long-term human hematopoiesis by implantation of a human adult bone fragment. Nine to 12 weeks posttransplantation, huma...

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Bibliographic Details
Main Authors: Frédérique Hubin, Chantal Humblet, Zakia Belaid, Roland Greimers, Jacques Boniver, Albert Thiry, Marie-Paule Defresne
Format: Article
Language:English
Published: SAGE Publishing 2004-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004783983387