Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope

Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope

ABSTRACTMimotope, a kind of peptide vaccine, is developed to bind natural receptor and inhibit the downstream signaling. We have demonstrated that the vaccination of Tocilizumab mimotopes could alleviate the renal fibrosis by interfering with both IL-6 and ferroptosis signaling. However, the effect...

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Bibliographic Details
Main Authors: Jin Guo, Lin Yang, Haoming Song, Li Bai
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Pulmonary fibrosis
lipid peroxidation
fibroblast
Tocilizumab
mimotope
IL-6
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2319965

Internet

https://www.tandfonline.com/doi/10.1080/21645515.2024.2319965

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