Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

Osteopontin (OPN) is an important component in both bone and blood regulation, functioning as a bridge between the two. Previously, thrombin-cleaved osteopontin (trOPN), the dominant form of OPN in adult bone marrow (BM), was demonstrated to be a critical negative regulator of adult hematopoietic st...

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Bibliographic Details
Main Authors: Huimin Cao, Benjamin Cao, Chad K. Heazlewood, Melanie Domingues, Xuan Sun, Emmanuel Debele, Narelle E. McGregor, Natalie A. Sims, Shen Y. Heazlewood, Susan K. Nilsson
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
osteopontin
fetal
hematopoietic stem cells
secreted phosphoprotein 1
Online Access:https://www.mdpi.com/2073-4409/8/9/985

Internet

https://www.mdpi.com/2073-4409/8/9/985

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