High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition

High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition

<p>Abstract</p> <p>Background</p> <p>Smad4 is a tumour suppressor frequently inactivated in pancreatic and colorectal cancers. We have recently reported loss of Smad4 in every fourth carcinoma of the uterine cervix. Smad4 transmits signals from the TGF-β superfamily of...

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Bibliographic Details
Main Authors: Schwarz Elisabeth, Hoppe Sabine, Eilert-Micus Christina, Zapatka Marc, Klein-Scory Susanne, Schmiegel Wolff, Hahn Stephan A, Schwarte-Waldhoff Irmgard
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/209

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http://www.biomedcentral.com/1471-2407/7/209

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