The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry

The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry

Abstract To enter epithelial cells, the obligate intracellular pathogen Chlamydia pneumoniae secretes early effector proteins, which bind to and modulate the host-cell’s plasma membrane and recruit several pivotal endocytic host proteins. Here, we present the high-resolution structure of an entry-re...

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Bibliographic Details
Main Authors: Fabienne Kocher, Violetta Applegate, Jens Reiners, Astrid Port, Dominik Spona, Sebastian Hänsch, Amin Mirzaiebadizi, Mohammad Reza Ahmadian, Sander H. J. Smits, Johannes H. Hegemann, Katja Mölleken
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51681-3

Internet

https://doi.org/10.1038/s41467-024-51681-3

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