Epithelial Ablation of Miro1/Rhot1 GTPase Augments Lung Inflammation by Cigarette Smoke

Mitochondrial quality control is sustained by Miro1 (Rhot1), a calcium-binding membrane-anchored GTPase during mitophagy. The exact mechanism that operates the interaction of Miro1 with mitophagy machinery and their role in cigarette smoke (CS)-induced mitochondrial dysfunction that often results in...

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Bibliographic Details
Main Authors: Shikha Sharma, Qixin Wang, Thivanka Muthumalage, Irfan Rahman
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pathophysiology
Subjects:
Online Access:https://www.mdpi.com/1873-149X/28/4/33