Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular Targets

Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular Targets

Obesity, characterized by excessive body fat, is closely linked to endoplasmic reticulum (ER) stress, leading to insulin resistance and type 2 diabetes. Inflammatory pathways like c-Jun N-terminal kinase (JNK) worsen insulin resistance, impacting insulin signaling. Moreover, ER stress plays a substa...

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Bibliographic Details
Main Authors: Joud AlBashtawi, Hend Al-Jaber, Sara Ahmed, Layla Al-Mansoori
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Biomedicines
Subjects:
endoplasmic reticulum
obesity
adipose tissue
cancer
Online Access:https://www.mdpi.com/2227-9059/12/4/793

Internet

https://www.mdpi.com/2227-9059/12/4/793

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