Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model

PURPOSEUse of oral sorafenib, an antiangiogenic chemotherapeutic agent for hepatocellular carcinoma (HCC), is limited by an unfavorable side effect profile. Transarterial chemoembolization (TACE) employs targeted intravascular drug administration, and has potential as a novel sorafenib delivery meth...

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Bibliographic Details
Main Authors: Ahmad Parvinian, Leigh C. Casadaban, Zane Z. Hauck, Richard B. van Breemen, Ron C. Gaba
Format: Article
Language:English
Published: Galenos Publishing House 2015-05-01
Series:Diagnostic and Interventional Radiology
Online Access: http://www.dirjournal.org/archives/archive-detail/article-preview/pharmacokinetic-study-of-conventional-sorafenib-ch/55820