MiR-125b-5p ameliorates hypoxia/reoxygenation-induced endothelial cell dysfunction and attenuates reduced uterine perfusion pressure-induced hypertension in pregnant rats via targeting BMF

MiR-125b-5p ameliorates hypoxia/reoxygenation-induced endothelial cell dysfunction and attenuates reduced uterine perfusion pressure-induced hypertension in pregnant rats via targeting BMF

Background and Purpose MicroRNA-125b-5p (miR-125b-5p) is downregulated in patients with gestational hypertension signs. However, the role of miR-125b-5p in pregnancy-induced hypertension (PIH) remains unknown. Methods The human placental microvascular endothelial cells (HPMECs) have undergone hypoxi...

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Bibliographic Details
Main Authors: Haoyu Zheng, Zhou Yu, Hairong Wang, Hongxue Liu, Xiaoqin Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Hypertension in Pregnancy
Subjects:
mir-125b-5p
bmf
human placental microvascular endothelial cells
pregnancy-induced hypertension
Online Access:http://dx.doi.org/10.1080/10641955.2022.2036753

Internet

http://dx.doi.org/10.1080/10641955.2022.2036753

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