Development and evaluation of 89Zr-trastuzumab for clinical applications

Objective(s): Due to the suitable physical characteristics of 89Zr as a PET radionuclide and affinity of Trastuzumab monoclonal antibody against HER2, [89Zr]Zr-Trastuzumab was prepared and went through preclinical evaluations for ultimate human applications.Methods: 89Zr was produced by using 89Y(p,...

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Bibliographic Details
Main Authors: Fatemeh Mohammadpour-Ghazi, Hassan Yousefnia, GhasemAli Divband, Samaneh Zolghadri, Behrouz Alirezapour, Fatemeh Shakeri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-06-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
Subjects:
Online Access:https://aojnmb.mums.ac.ir/article_21555_01d733f3d8b4eb2b610db538c0463c4a.pdf