MicroRNA-495 inhibits the high glucose-induced inflammation, differentiation and extracellular matrix accumulation of cardiac fibroblasts through downregulation of NOD1

MicroRNA-495 inhibits the high glucose-induced inflammation, differentiation and extracellular matrix accumulation of cardiac fibroblasts through downregulation of NOD1

Abstract Background MicroRNAs (miRNAs) have physiological and pathophysiological functions that are involved in the regulation of cardiac fibrosis. This study aimed to investigate the effects of miR-495 on high glucose-induced cardiac fibrosis in human cardiac fibroblasts (CFs) and to establish the...

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Bibliographic Details
Main Authors: Xiaowei Wang, Haiying Jin, Shifeng Jiang, Yanlan Xu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
MicroRNA-495
Human cardiac fibroblasts
High glucose
Cardiac fibrosis
NOD1
Online Access:http://link.springer.com/article/10.1186/s11658-018-0089-x

Internet

http://link.springer.com/article/10.1186/s11658-018-0089-x

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