En route to photoaffinity labeling of the bacterial lectin FimH

Mannose-specific adhesion of Escherichia coli bacteria to cell surfaces, the cause of various infections, is mediated by a fimbrial lectin, called FimH. X-ray studies have revealed a carbohydrate recognition domain (CRD) on FimH that can complex α-D-mannosides. However, as the precise nature of the...

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Bibliographic Details
Main Authors: Thisbe K. Lindhorst, Michaela Märten, Andreas Fuchs, Stefan D. Knight
Format: Article
Language:English
Published: Beilstein-Institut 2010-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.91