Mondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila.

Sugars are important nutrients for many animals, but are also proposed to contribute to overnutrition-derived metabolic diseases in humans. Understanding the genetic factors governing dietary sugar tolerance therefore has profound biological and medical significance. Paralogous Mondo transcription f...

Full description

Bibliographic Details
Main Authors: Essi Havula, Mari Teesalu, Tuulia Hyötyläinen, Heini Seppälä, Kiran Hasygar, Petri Auvinen, Matej Orešič, Thomas Sandmann, Ville Hietakangas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3616910?pdf=render