Crohn’s disease recurrence updates: first surgery vs. surgical relapse patients display different profiles of ileal microbiota and systemic microbial-associated inflammatory factors

Background and aimsCrohn’s disease (CD) pathogenesis is still unclear. Remodeling in mucosal microbiota and systemic immunoregulation may represent an important component in tissue injury. Here, we aim to characterize the ileal microbiota in both pathological and healthy settings and to evaluate the...

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Bibliographic Details
Main Authors: Edda Russo, Lorenzo Cinci, Leandro Di Gloria, Simone Baldi, Mario D’Ambrosio, Giulia Nannini, Elisabetta Bigagli, Lavinia Curini, Marco Pallecchi, Donato Andrea Arcese, Stefano Scaringi, Cecilia Malentacchi, Gianluca Bartolucci, Matteo Ramazzotti, Cristina Luceri, Amedeo Amedei, Francesco Giudici
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.886468/full