ELAVL2 loss promotes aggressive mesenchymal transition in glioblastoma
Abstract Glioblastoma (GBM), the most lethal primary brain cancer, exhibits intratumoral heterogeneity and molecular plasticity, posing challenges for effective treatment. Despite this, the regulatory mechanisms underlying such plasticity, particularly mesenchymal (MES) transition, remain poorly und...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-024-00566-1 |