ELAVL2 loss promotes aggressive mesenchymal transition in glioblastoma

Abstract Glioblastoma (GBM), the most lethal primary brain cancer, exhibits intratumoral heterogeneity and molecular plasticity, posing challenges for effective treatment. Despite this, the regulatory mechanisms underlying such plasticity, particularly mesenchymal (MES) transition, remain poorly und...

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Bibliographic Details
Main Authors: Yona Kim, Ji Hyeon You, Yeonjoo Ryu, Gyuri Park, Urim Lee, Hyo Eun Moon, Hye Ran Park, Chang W. Song, Ja-Lok Ku, Sung-Hye Park, Sun Ha Paek
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00566-1