Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes
Abstract Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-loxP system is widely used as an integral experimental tool for generating the conditional. This system ha...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | Laboratory Animal Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.5625/lar.2018.34.4.147 |