Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes

Abstract Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-loxP system is widely used as an integral experimental tool for generating the conditional. This system ha...

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Bibliographic Details
Main Authors: Hyeonhui Kim, Minki Kim, Sun-Kyoung Im, Sungsoon Fang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.5625/lar.2018.34.4.147