Low-Dose Acetylsalicylic Acid and Mitochondria-Targeted Antioxidant Mitoquinone Attenuate Non-Alcoholic Steatohepatitis in Mice

Low-Dose Acetylsalicylic Acid and Mitochondria-Targeted Antioxidant Mitoquinone Attenuate Non-Alcoholic Steatohepatitis in Mice

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. NAFLD can evolve from simple fatty liver to non-alcoholic steatohepatitis (NASH), and ultimately, to cirrhosis. Inflammation and oxidative stress, promoted by mitochondrial dysfunction, play a crucial role in the ons...

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Bibliographic Details
Main Authors: Saadet Turkseven, Cristian Turato, Gianmarco Villano, Mariagrazia Ruvoletto, Maria Guido, Massimo Bolognesi, Patrizia Pontisso, Marco Di Pascoli
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
liver injury
steatohepatitis
oxidative stress
mitochondria dysfunction
Online Access:https://www.mdpi.com/2076-3921/12/4/971

Internet

https://www.mdpi.com/2076-3921/12/4/971

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