The effect of HLA-DRB1*04:01 on a mouse model of atherosclerosis

Objectives: HLA-DRB1 is associated with an increased risk of cardiovascular disease in patients with rheumatoid arthritis (RA). This study aimed to determine the effect of HLA-DRB1 on atherosclerotic cardiovascular disease (ASCVD) using a novel mouse model. Methods: Mice transgenic for HLA-DRB1*04:0...

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Bibliographic Details
Main Authors: Garth Blackler, James Akingbasote, Ewa Cairns, Christopher Howlett, Patti Kiser, Lillian Barra
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Translational Autoimmunity
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909023000163