Hydroxycitric acid inhibits kidney stone through crystallization regulation and reduction of hyperoxalate-induced lipotoxicity

Hydroxycitric acid inhibits kidney stone through crystallization regulation and reduction of hyperoxalate-induced lipotoxicity

Kidney stone is a urinary system disease with a high incidence, and effective stone drugs are limited. Hydroxycitric acid (HCA), mainly found in Garcinia cambogia and Hibiscus sabdariffa, can reduce body weight and calcium salt deposition. In this study, we explored the molecular mechanisms of HCA i...

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Bibliographic Details
Main Authors: Yi-Han Zhang, Jun-Yi Xian, Shu-Jue Li, Chun-Yao Li, Bang-Xian Yu, Qing Liang, Ling-Hong Huang, Guo-Hua Zeng, Xin-Yuan Sun
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Functional Foods
Subjects:
Kidney stone
Lipotoxicity
Oxidative damage
Hydroxycitric acid
PPARα
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623001615

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http://www.sciencedirect.com/science/article/pii/S1756464623001615

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