Abnormal Circulating Maternal miRNA Expression Is Associated with a Low (<4%) Cell-Free DNA Fetal Fraction

The present pilot study investigates whether an abnormal miRNA profile in NIPT plasma samples can explain the finding of a low cell-free DNA (cfDNA) fetal fraction (cfDNAff) in euploid fetuses and non-obese women. Twelve women who underwent neoBona<sup>®</sup> NIPT with a normal fetal ka...

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Bibliographic Details
Main Authors: Graziano Santoro, Cristina Lapucci, Marco Giannoccaro, Simona Caporilli, Martina Rusin, Anna Seidenari, Maurizio Ferrari, Antonio Farina
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/11/2108