Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, poses a great threat to human health. With the emergence of drug resistant Mtb strains, new therapeutics are desperately needed. As iron is critical to the growth and survival of Mtb, mechanisms through which Mtb acquires host ir...

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Bibliographic Details
Main Authors: Rodger de Miranda, Bonnie J Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Mark Arbing, Paul J Sieminski, Kadamba Papavinasasundaram, Sumer Abdul-Hafiz, Sum Chan, Christopher M Sassetti, Sabine Ehrt, Celia W Goulding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011650&type=printable