Investigating the tumor-immune microenvironment through extracellular vesicles from frozen patient biopsies and 3D cultures

Melanomas are highly immunogenic tumors that have been shown to activate the immune response. Nonetheless, a significant portion of melanoma cases are either unresponsive to immunotherapy or relapsed due to acquired resistance. During melanomagenesis, melanoma and immune cells undergo immunomodulato...

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Bibliographic Details
Main Authors: Ala’a Al Hrout, Mitchell P. Levesque, Richard Chahwan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176175/full