Investigating the tumor-immune microenvironment through extracellular vesicles from frozen patient biopsies and 3D cultures
Melanomas are highly immunogenic tumors that have been shown to activate the immune response. Nonetheless, a significant portion of melanoma cases are either unresponsive to immunotherapy or relapsed due to acquired resistance. During melanomagenesis, melanoma and immune cells undergo immunomodulato...
Main Authors: | Ala’a Al Hrout, Mitchell P. Levesque, Richard Chahwan |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176175/full |
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