Using chitosan and xanthan gum mixtures as excipients in controlled release formulations of ambroxol HCl - in vitro drug release and swelling behavior

Using chitosan and xanthan gum mixtures as excipients in controlled release formulations of ambroxol HCl - in vitro drug release and swelling behavior

Directly compressed matrices were produced using a binary mixture of different chitosan (CH) and xanthan gum (XG) ratios. These hydrophilic excipients were used to control the release of ambroxol HCl. CH and XG were investigated at three ratios of 1:1, 1:4 and 4:1. Mucosolvan LA® was used as a comme...

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Bibliographic Details
Main Authors: Faisal Al-Akayleh, Mayyas Al Remawi, Mutaz S. Salemc, Adnan Badwan
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-10-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/951-using-chitosan-and-xanthan-gum-mixtures-as-excipients-in-controlled-release-formulations-of-ambroxol-hcl-in-vitro-drug-release-and-swelling-behavior

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https://jefc.scholasticahq.com/article/951-using-chitosan-and-xanthan-gum-mixtures-as-excipients-in-controlled-release-formulations-of-ambroxol-hcl-in-vitro-drug-release-and-swelling-behavior

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