Using chitosan and xanthan gum mixtures as excipients in controlled release formulations of ambroxol HCl - in vitro drug release and swelling behavior
Directly compressed matrices were produced using a binary mixture of different chitosan (CH) and xanthan gum (XG) ratios. These hydrophilic excipients were used to control the release of ambroxol HCl. CH and XG were investigated at three ratios of 1:1, 1:4 and 4:1. Mucosolvan LA® was used as a comme...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
International Pharmaceutical Excipients Council
2016-10-01
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Series: | Journal of Excipients and Food Chemicals |
Online Access: | https://jefc.scholasticahq.com/article/951-using-chitosan-and-xanthan-gum-mixtures-as-excipients-in-controlled-release-formulations-of-ambroxol-hcl-in-vitro-drug-release-and-swelling-behavior |