An Intratumor Heterogeneity-Related Signature for Predicting Prognosis, Immune Landscape, and Chemotherapy Response in Colon Adenocarcinoma

An Intratumor Heterogeneity-Related Signature for Predicting Prognosis, Immune Landscape, and Chemotherapy Response in Colon Adenocarcinoma

BackgroundColon adenocarcinoma (COAD) is a frequent malignancy of the digestive system with a poor prognosis and high mortality rate worldwide. Intratumor heterogeneity (ITH) is associated with tumor progression, poor prognosis, immunosuppression, and therapy resistance. However, the relationship be...

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Bibliographic Details
Main Authors: Cong Liu, Dingwei Liu, Fangfei Wang, Jun Xie, Yang Liu, Huan Wang, Jianfang Rong, Jinliang Xie, Jinyun Wang, Rong Zeng, Feng Zhou, Yong Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
colon adenocarcinoma
intratumor heterogeneity
prognostic
tumor microenvironment
chemotherapy response
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.925661/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.925661/full

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