A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle

Abstract Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the continuous cycle of infection between the human host and the mosquito vector. Domain 1 (D1) of Pfs230 is a leading TBV candidate and comprises the majority of transmission-reducing activity (TRA) elici...

Full description

Bibliographic Details
Main Authors: Nichole D. Salinas, Rui Ma, Thayne H. Dickey, Holly McAleese, Tarik Ouahes, Carole A. Long, Kazutoyo Miura, Lynn E. Lambert, Niraj H. Tolia
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00709-8