Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone

Abstract Background The aqueous environment directs the protein folding process towards the generation of micelle-type structures, which results in the exposure of hydrophilic residues on the surface (polarity) and the concentration of hydrophobic residues in the center (hydrophobic core). Obtaining...

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Bibliographic Details
Main Authors: Irena Roterman, Katarzyna Stapor, Leszek Konieczny
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05545-0