Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone
Abstract Background The aqueous environment directs the protein folding process towards the generation of micelle-type structures, which results in the exposure of hydrophilic residues on the surface (polarity) and the concentration of hydrophobic residues in the center (hydrophobic core). Obtaining...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-023-05545-0 |