Synthesis and Antiviral Activity of Conformational Analogues of Leucamide A

Synthesis and Antiviral Activity of Conformational Analogues of Leucamide A

In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues were prepared by replacing the Pro-Leu dipeptide in the molecule with various amino acids. The amino acids used were of 2 to 6 carbons. The resu...

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Bibliographic Details
Main Authors: Wen-Long Wang, Hai-Jun Chen, Wei-Ping Ma, Min Gu, Min-Zhi Fan, Jing-Ya Li, Bainian Feng, Fa-Jun Nan
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
&#160
leucamide A
conformational analogues
synthesis
anti-influenza virus A
Online Access:http://www.mdpi.com/1420-3049/17/12/14522

Internet

http://www.mdpi.com/1420-3049/17/12/14522

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